PhD position in the group of Leo van Grunsven Vrije Universiteit Brussel (VUB), Belgium
We are seeking one PhD candidate to work in a team consisting of multiple PhD students and postdocs and in collaboration with groups of the KULeuven and UGent. Our aim is to establish human pluripotent stem cell derived 3D liver culture systems. The candidate will be responsible for improving the currently available pluripotent stem cell-derived HSCs by screening RNA-seq data for potential signaling pathways that could improve the stellate cell phenotype. The optimized stem cell derived HSCs will be tested in vitro using 3D co-cultures with stem cell-derived hepatocytes and in vivo using mouse models of liver disease.
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